منابع مشابه
A mouse model for cystinuria type I.
Cystinuria, one of the most common inborn errors of metabolism in humans, accounts for 1-2% of all cases of renal lithiasis. It is caused by defects in the heterodimeric transporter system rBAT/b0,+AT, which lead to reduced reabsorption of cystine and dibasic amino acids through the epithelial cells of the renal tubules and the intestine. In an N-ethyl-N-nitrosourea mutagenesis screen for reces...
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Cystinuria is an aminoaciduria caused by mutations in the genes that encode the two subunits of the amino acid transport system b0,+, responsible for the renal reabsorption of cystine and dibasic amino acids. The clinical symptoms of cystinuria relate to nephrolithiasis, due to the precipitation of cystine in urine. Mutations in SLC3A1, which codes for the heavy subunit rBAT, cause cystinuria t...
متن کاملA diet-induced mouse model for glutaric aciduria type I.
In the autosomal recessive human disease, glutaric aciduria type I (GA-1), glutaryl-CoA dehydrogenase (GCDH) deficiency disrupts the mitochondrial catabolism of lysine and tryptophan. Affected individuals accumulate glutaric acid (GA) and 3-hydroxyglutaric acid (3-OHGA) in the serum and often suffer acute striatal injury in childhood. Prior attempts to produce selective striatal vulnerability i...
متن کاملa cauchy-schwarz type inequality for fuzzy integrals
نامساوی کوشی-شوارتز در حالت کلاسیک در فضای اندازه فازی برقرار نمی باشد اما با اعمال شرط هایی در مسئله مانند یکنوا بودن توابع و قرار گرفتن در بازه صفر ویک می توان دو نوع نامساوی کوشی-شوارتز را در فضای اندازه فازی اثبات نمود.
15 صفحه اولA new model of (I+S)-type preconditioner for system of linear equations
In this paper, we design a new model of preconditioner for systems of linear equations. The convergence properties of the proposed methods have been analyzed and compared with the classical methods. Numerical experiments of convection-diffusion equations show a good im- provement on the convergence, and show that the convergence rates of proposed methods are superior to the other modified itera...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2003
ISSN: 1460-2083
DOI: 10.1093/hmg/ddg189